The "active ingredients package" is common to all products in the SAIFER Range which require bacteria and virus control capability.

The package is based around two new generation quaternary ammonium products whose spectrum of activity has been greatly extended beyond the level of efficacy normally associated with this group of compounds, by synergy and potentiating agents. By making use of this enhanced activity it has been possible to use very low concentrations of active ingredients in formulations where they would not normally be considered. As a consequence of this it has been possible to incorporate the package into products that are applied to skin and so achieve a performance in that area which has not been possible before, particularly with respect to virucidal activity.

The specific advantages to the SAIFER Range can be seen by reviewing the appropriate product information sheet but the performance data tabulated below shows how extensive the efficacy of this particular "active package" is.

Staphylococcus aureus ATC 6538 (3 separate multi-resistant strains)

• Skin infections such as post operative wound infections, cellulitis, boils, carbuncles, impetigo. Both community and hospital acquired infections such as blood poisoning, endocarditis, meningitis, pneumonia and osteomyelitis.

Pseudomonas aeruginosa (multi-resistant strain)

• Very serious hospital acquired infections leading to infant diarrhoea, eye infections, burn infections, a complication in cystic fibrosis, folliculitis, osteomyelitis and malignant external otitis.

Spores of Bacillus subtilis

• Non-pathogenic strain of spore forming bacteria. Used as safe laboratory test organism.

Clostridium difficile

• Pseudomembranous colitis, often following antibiotic therapy and especially in older patients. Can cause severe outbreaks of diarrhoea with 10% mortality.

Escherichia coli (including MRSA and other multi-resistant strains)

• "Travellers diarrhoea", urinary tract infections, terminal septicaemia and infant diarrhoea. New strains cause fatal toxaemia through food poisoning and or chronic kidney failure in survivors.

Mycobacterium tuberculosis

• Cause of classical Tuberculosis. Increasing prevalence with recent increases in number of immunocompromised patients and those "sleeping rough". New antibiotic resistant strains are causing major concern.

Mycobacterium avium-intracellulare

• Now a significant cause of Tuberculosis in immunocompromised patients and a major concern in differential diagnosis.

Klebsiella pneumoniae

• Pneumonia, infant diarrhoea and urinary tract infections.

Salmonella choleraesuis

• Gastroenteritis, septicaemia (blood poisoning), arthritis.

Salmonella enteritidis

• Food poisoning, blood poisoning, people can become carriers.

Salmonella typhi

• Typhoid fever.

Salmonella typhimurium

• Food poisoning, enters blood and can cause chronic gall bladder infections.

Staphylococcus epidermidis

• Bacteraemia, infective endocarditis, peritonitis associated with dialysis and genitourinary tract infections.

Streptococcus faecalis (multi-resistant strain)

• Group D occurs in the neonatal period. Anatomical defects in the central nervous system, neurological intervention, endocarditis, urinary tract infections may lead to meningitis.

Streptococcus pyogenes

• Beta Haemolytic Group A. Transmission from person to person usually from close contact by an asymptomatic carrier colonised in the nasopharynx, skin, vagina or rectum. It may be transmitted by contaminated food. Causes pharyngitis, tonsillitis, sinusitis, arthritis, etc. After five weeks of pharyngeal infection, rheumatic fever, scarlet fever, or impetigo may occur.

Acinetobacter calcoaceticus

• Hospital acquired infections in compromised patients leading to septicaemia, meningitis, abscesses and urinary tract infections.

Bordatella bronchiseptica

• Part of the cause of "Kennel Cough" in dogs.

Enterobacter aerogenes & cloacae

• Hospital acquired infections; bacteraemia, urinary tract infection, post-surgical wound infection.

Fusobacterium necrophorum

• Hoof rot in cattle, sheep and horses.

Listeria monocytogenes

• Food poisoning, listeriosis, meningitis and abortion.

Pasteurella multocida

• Fowl cholera. The cause of human cat and dog bight "fever".

Proteus mirabilis & vulgaris

• Urinary tract infections, infant diarrhoea and respiratory tract infections.

Serratia marcescens

• Cystitis, blood and central nervous system infections.

Shigella flexeri & sonnei

• Bacillary dysentery with severe cramping abdominal pain and diarrhoea with blood and mucous.

Chlamydia psittaci

• Fatal pneumonia in humans, usually caught from clinically normal carrier birds. Can cause abortion in domestic animals.

Adenovirus

• Causes a low incidence of respiratory infections.

Avian Bronchitis Virus

• Acute, rapidly spreading respiratory infection of chickens. Causes abnormal egg shells.

Canine Distemper Virus

• Highly infectious disease of dogs causing fever, gastrointestinal and respiratory problems, and often nervous symptoms in survivors.

Canine Parvovirus

• Diarrhoea, vomiting, fever and loss of appetite in dogs. Very high mortality when it first arrives in an area.

Feline Leukaemia Virus

• Related to lymphosarcoma. Passed in saliva from cat to cat.

Feline Panleukopaenia Virus

• Causes cat infections leading to fever, decreased white blood cells, brain lesions in embryos and heart lesions in young kittens.

Feline Picornavirus

• Cat respiratory tract infections, conjunctivitis and vesicles in the mouth of cats.

Hepatitis B Virus

• Human hepatitis.

Herpes Simplex Type 1 (HSV 1)

• Blisters and canker sores caused by colds.

Herpes Simplex Type 2

• Lesions on penis, urethra, vulva, vagina and skin of buttocks.

Human Immunodeficiency Virus (HIV)

• Severe damage to human immune system.

Infectious Bovine Rhinotracheitis Virus

• Upper respiratory tract infection in cattle and may also cause bronchial pneumonia, abortions and still births. Encephalitis in 2-3 month old calves, oral and gastric lesions in new-borns.

Influenza Virus Type A

• Acute respiratory disease in epidemic form. Transmitted from person to person by coughing and sneezing, but hands have recently been identified as a major route of transmission.

Porcine Parvovirus

• Abortions in pigs.

Pseudorabies Virus

• Acute central nervous system disease in mammals, especially pigs. Fatal to domestic pets.

Rabies Virus

• Fatal nervous disease. Humans usually contract the disease through bights from infected animals.

Respiratory Syncytial Virus

• Highly contagious cause of pneumonia and bronchiolitis in small children.

Rubella Virus

• Cause of German Measles.

Transmissible Gastroenteritis

• Profuse vomiting and diarrhoea in pigs with high mortality in new-born.

Vaccinia Virus

• Pox virus used to immunise man against small pox.

Trichophyton mentagrophytes

• Fungal cause of Athletes foot.

Candida albicans

• Vaginal infections. Normal flora in the throat.

Aspergillus niger

• May cause aspergillosis, pneumonia, skin infections and ear infections.